Toph Beifong - Avatar: The Last Airbender - Blindness
Nagisa Furukawa - Clannad - Unnamed Severe Illness
Mitsuki Kouyama - Full Moon O Sagashite - Throat Cancer
Almost Every Character - Katawa Shoujo - Bilateral Below-Knee Amputation, Bilateral Above-Elbow Amputation, Burn & Trauma Victim, Blindness, Deafness
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